ICSI is typically advised for:

• Low sperm count or poor sperm motility

• Abnormal sperm morphology

• Previous IVF fertilization failures

• Sperm retrieval via TESA/PESA

• Use of frozen or donor sperm

• Maintain a nutrient-rich diet with antioxidants

• Avoid alcohol, smoking, and excessive caffeine

• Take prescribed supplements (folic acid, CoQ10, Vitamin D)

• Manage stress through yoga or meditation

• Ensure 7-8 hours of quality sleep nightly

1. Ovarian Stimulation: Hormone injections (8-14 days) to develop multiple follicles.

2. Egg Retrieval: Ultrasound-guided needle aspiration under sedation (20-30 min procedure).

3. Sperm Collection: Fresh sample or surgical extraction (TESA/PESA) if needed.

4. Sperm Preparation: High-mobility sperm selected using density gradient centrifugation.

5. Micromanipulation: Single sperm immobilized and injected into each mature egg using microscopic tools.

6. Embryo Culture: Fertilized eggs monitored for 3-5 days in controlled lab conditions.

7. Embryo Transfer: Best-quality embryo(s) transferred to uterus via thin catheter.

8. Luteal Support: Progesterone supplements to support implantation.

Common Symptoms:

• Mild cramping/spotting (1-2 days post-transfer)

• Bloating from ovarian stimulation

• Breast tenderness due to progesterone

Do's: Light walking, hydration, prescribed medications

Don'ts: Heavy lifting, hot baths, unprotected intercourse

• Clinic Expertise: ART-registered labs with experienced embryologists

• Personalization: Tailored hormone protocols based on AMH/FSH levels

• Advanced Techniques: Time-lapse embryo monitoring, PGT-A testing

• Uterine Receptivity: Endometrial scratching or PRP if needed

ICSI has revolutionized treatment for male factor infertility, with success rates up to 50% per cycle in women under 35. Choosing a clinic with cutting-edge technology and personalized care maximizes your chances. Consult a fertility specialist to discuss if ICSI aligns with your unique needs.