How Many Times Can a Couple Undergo IUI Treatment?

Intrauterine Insemination (IUI) is often one of the first assisted reproductive technologies (ART) used for treating infertility. IUI involves injecting prepared sperm directly into the uterus, bypassing the cervix—a common obstacle for sperm to reach the egg. This procedure is typically recommended for couples dealing with male infertility factors such as low sperm motility or count, incompatibility between sperm and cervical mucus, or unexplained infertility.

For women under the age of 35, the average success rate for each IUI cycle ranges from 10% to 20%. With each attempt, the cumulative chance of becoming pregnant increases, leading to a 30% to 60% chance of success after three IUI cycles. It's important to note that these percentages are influenced by several factors, including the mother’s age and whether she has ovulatory issues.

Combining IUI with ovulation induction therapy, which uses medications like letrozole, clomid, or injectable hormones to stimulate ovulation, can nearly double the chances of conception.

In most cases, IUI requires multiple cycles to achieve success. Typically, a doctor may recommend three to six cycles of IUI before considering more advanced treatments like IVF. Transitioning from IUI to IVF sooner can improve the chances of pregnancy for many couples. Consulting with a fertility expert can help determine the best course of action.

Discuss with your doctor and partner how many IUI attempts you want to undertake from the start. For some, three cycles may suffice, while others may feel that six or more attempts are necessary. This decision largely depends on your individual circumstances, finances, and the urgency of your treatment timeline.

IUI is a viable fertility treatment for many couples, but it may not be successful on the first try. Knowing when to persist with IUI or move to IVF can help couples navigate their fertility journey more effectively. It's always best to consult with a fertility professional for personalized advice.